1. What is Absolute Lymph Count?

The Absolute Lymphocyte Count (ALC) is a measurement of the actual number of lymphocyte cells in a microliter of blood. It's calculated by multiplying the total white blood cell count by the percentage of lymphocytes.

2. How Does the Calculator Work?

The calculator uses the ALC equation:

Where:

• \( Total\ WBC \) — Total white blood cell count (cells/μL)
• \( Lymphocytes \) — Percentage of lymphocytes in differential count (%)

Explanation: The equation converts the percentage of lymphocytes into an absolute count by factoring in the total white blood cell count.

3. Importance of ALC Calculation

Details: ALC is important for assessing immune function, monitoring chemotherapy patients, and evaluating various hematologic conditions like lymphopenia or lymphocytosis.

4. Using the Calculator

Tips: Enter total WBC count in cells/μL and lymphocyte percentage. Both values must be valid (WBC > 0, lymphocytes between 0-100%).

5. Frequently Asked Questions (FAQ)

Q1: What is a normal ALC range?
A: Normal range is typically 1,000-4,800 cells/μL in adults, though ranges may vary slightly by laboratory.

Q2: When is ALC clinically significant?
A: Clinically significant when below 1,000 cells/μL (lymphopenia) or above 4,800 cells/μL (lymphocytosis).

Q3: How does ALC relate to immune function?
A: ALC reflects the body's lymphocyte population which is crucial for adaptive immunity. Low counts increase infection risk.

Q4: Are there limitations to ALC interpretation?
A: Yes, ALC should be interpreted in clinical context along with differential counts and other lab values.

Q5: How often should ALC be monitored?
A: Frequency depends on clinical situation (e.g., weekly during chemotherapy, periodically in HIV management).