1. What is Iron Saturation?

Iron saturation measures the percentage of transferrin (the main iron transport protein in blood) that is saturated with iron. It's calculated by dividing serum iron by total iron-binding capacity (TIBC) and multiplying by 100.

2. How Does the Calculator Work?

The calculator uses the iron saturation formula:

Where:

• \( Blood\_iron \) — Serum iron concentration (μg/dL)
• \( TIBC \) — Total iron-binding capacity (μg/dL)

Explanation: The formula shows what percentage of available iron-binding sites on transferrin are actually occupied by iron.

3. Importance of Iron Saturation

Details: Iron saturation helps diagnose iron deficiency or iron overload conditions. Low saturation suggests iron deficiency, while high saturation may indicate hemochromatosis or iron poisoning.

4. Using the Calculator

Tips: Enter blood iron and TIBC values in μg/dL. Both values must be positive numbers. For accurate results, tests should be performed in the morning after fasting.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal iron saturation level?
A: Normal range is typically 20-50%. Values below 20% may indicate iron deficiency, while above 50% may suggest iron overload.

Q2: How does this differ from ferritin?
A: Ferritin measures iron stores, while saturation measures circulating iron bound to transferrin. Both tests are often ordered together.

Q3: When should I get my iron saturation tested?
A: Testing is recommended when symptoms suggest anemia, iron overload, or to monitor treatment for these conditions.

Q4: Can medications affect iron saturation?
A: Yes, iron supplements, oral contraceptives, and certain other medications can affect results. Inform your doctor about all medications.

Q5: What if my TIBC is high but saturation is low?
A: This pattern typically indicates iron deficiency anemia, where the body produces more transferrin to try to capture more iron.