1. What is THC Half Life?

The half-life (HL) of THC (tetrahydrocannabinol) is the time required for the concentration of THC in the body to be reduced by half. It's an important pharmacokinetic parameter that helps determine how long THC remains in the system.

2. How Does the Calculator Work?

The calculator uses the THC half-life equation:

Where:

• \( HL \) — Half-life (days)
• \( Vd \) — Volume of distribution (L)
• \( Cl \) — Clearance (L/day)
• 0.693 — Natural logarithm of 2 (ln(2))

Explanation: The equation shows that half-life is directly proportional to volume of distribution and inversely proportional to clearance.

3. Importance of THC Half Life Calculation

Details: Understanding THC half-life is crucial for determining detection windows in drug tests, dosing regimens, and understanding how long effects might last in different individuals.

4. Using the Calculator

Tips: Enter volume of distribution in liters (L) and clearance in liters per day (L/day). Both values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What is the typical half-life of THC?
A: THC half-life varies widely but is typically 1-10 days in occasional users and up to 13 days in chronic users due to accumulation in fat tissue.

Q2: Why does THC have such a long half-life?
A: THC is highly lipophilic (fat-soluble) and accumulates in fat tissues, leading to slow release back into circulation.

Q3: How does frequency of use affect half-life?
A: Chronic use increases half-life due to accumulation in fat tissues and possible enzyme saturation.

Q4: What factors influence THC clearance?
A: Metabolism (mainly CYP2C9), body fat percentage, hydration, exercise, and individual metabolic differences.

Q5: How does this relate to drug test detection?
A: While THC may be eliminated from blood quickly, metabolites can be detected in urine for days to weeks depending on usage patterns.