1. What is Transferrin Saturation (TSAT)?

Transferrin saturation (TSAT) measures the percentage of iron-binding sites on transferrin that are occupied by iron. It's an important indicator of iron status in the body, particularly for assessing iron deficiency or iron overload.

2. How Does the Calculator Work?

The calculator uses the TSAT equation:

Where:

• \( Iron \) — Serum iron concentration (μg/dL)
• \( TIBC \) — Total iron-binding capacity (μg/dL)

Explanation: The equation calculates what percentage of the total iron-binding capacity is actually being used by iron.

3. Importance of TSAT Calculation

Details: TSAT helps diagnose iron disorders - low TSAT suggests iron deficiency while high TSAT may indicate iron overload or hemochromatosis.

4. Using the Calculator

Tips: Enter serum iron and TIBC values in μg/dL. Both values must be positive numbers. For accurate results, testing should be done in the morning after fasting.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal TSAT range for men?
A: Typically 20-50%. Below 20% suggests iron deficiency, above 50% may indicate iron overload.

Q2: How does TSAT differ between men and women?
A: Women generally have lower normal ranges due to menstrual blood loss. This calculator is specifically calibrated for men's ranges.

Q3: When should TSAT be measured?
A: When evaluating anemia, suspected iron disorders, or monitoring iron therapy. Morning fasting samples are preferred.

Q4: What affects TSAT results?
A: Recent iron intake, inflammation, liver disease, and certain medications can affect results.

Q5: Is TSAT alone sufficient for diagnosis?
A: No, it should be interpreted with ferritin, hemoglobin, and clinical context for complete assessment.