Total Lymphocyte Count Formula:
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Total Lymphocyte Count (TLC) is a measure of the absolute number of lymphocytes in the blood, calculated from the white blood cell count and the percentage of lymphocytes. It's used to assess immune function and monitor various clinical conditions.
The calculator uses the TLC formula:
Where:
Explanation: The equation converts the relative percentage of lymphocytes into an absolute count by multiplying with the total WBC count.
Details: TLC is important for evaluating immune status, monitoring HIV progression, assessing nutritional status, and evaluating response to therapy in various conditions.
Tips: Enter WBC count in cells/μL and lymphocyte percentage (from differential count). Both values must be positive numbers (WBC > 0, Lymph % between 0-100).
Q1: What is a normal TLC range?
A: Normal range is typically 1,000-4,800 cells/μL in adults, but varies by age and laboratory standards.
Q2: What does a low TLC indicate?
A: Lymphopenia (low TLC) may indicate viral infections, malnutrition, autoimmune disorders, or immunodeficiency.
Q3: What does a high TLC indicate?
A: Lymphocytosis (high TLC) may suggest acute viral infections, chronic inflammatory conditions, or certain leukemias.
Q4: When should TLC be measured?
A: TLC is useful when evaluating suspected immune disorders, monitoring HIV/AIDS, or assessing nutritional status.
Q5: Are there limitations to TLC interpretation?
A: TLC should always be interpreted in clinical context along with other tests and patient history.