1. What is Total Lymphocyte Count?

Total Lymphocyte Count (TLC) is a measure of the absolute number of lymphocytes in the blood, calculated from the white blood cell count and the percentage of lymphocytes. It's an important parameter in assessing immune function in dogs.

2. How Does the Calculator Work?

The calculator uses the TLC formula:

Where:

• \( WBC \) — White blood cell count (cells/μL)
• \( Lymph\% \) — Percentage of lymphocytes in differential count
• \( TLC \) — Total lymphocyte count (cells/μL)

Explanation: The calculation converts the percentage of lymphocytes into an absolute count based on the total white blood cell count.

3. Importance of TLC Calculation

Details: TLC is crucial for evaluating immune status, diagnosing lymphopenia or lymphocytosis, and monitoring response to therapy in canine patients.

4. Using the Calculator

Tips: Enter WBC count in cells/μL and lymphocyte percentage (0-100%). Both values must be valid (WBC > 0, Lymph% between 0-100).

5. Frequently Asked Questions (FAQ)

Q1: What is a normal TLC range for dogs?
A: Normal TLC in dogs typically ranges between 1,000-4,800 cells/μL, but consult breed-specific references as values may vary.

Q2: When is TLC particularly important?
A: TLC is especially valuable in evaluating immune function in cases of suspected immunodeficiency, chronic infections, or during chemotherapy monitoring.

Q3: How does TLC differ from lymphocyte percentage?
A: While percentage shows relative proportion, TLC provides the absolute number of lymphocytes, which is more clinically meaningful.

Q4: What conditions cause low TLC in dogs?
A: Lymphopenia can occur with stress, corticosteroid administration, viral infections (e.g., parvovirus), or certain immune-mediated diseases.

Q5: What about high TLC values?
A: Lymphocytosis may occur with chronic inflammation, immune stimulation, or certain leukemias.